Services on the Circle, Central and Waterloo and City lines are suspended, while services on the other lines have been disrupted.
Members of the RMT and TSSA unions walked out at 1830BST on Sunday against plans to cut 800 ticket office jobs.
Transport for London said about 75% of stations on the network were open.
There is a good service on the Docklands Light Railway and London Overground.
A spokesman for TfL said they hoped to run a better service than last time the network was hit by a strike in September.
TfL is laying on 100 extra buses and has increased capacity for more than 10,000 extra river journeys and also delayed roadworks in an attempt to reduce travel disruption.
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Those who own bikes have been encouraged to cycle to work.
A similar walkout last month caused chaos on the Underground.
TfL pleaded with the unions to call off the strike, which it labelled "pointless", but the unions hit back by saying the planned job cuts would threaten safety on the network.
'Political attack'
On Sunday, RMT general secretary Bob Crow said: "We have warned repeatedly that TfL's cuts plans are playing fast and loose with safety and will turn the Tube into a death trap.
"We remain available for talks but the current cuts to jobs and safety must be halted before we have a tragedy on our hands."
London Underground's managing director, Mike Brown, said the unions were "intent on disruption".
He said: "Changing London Underground is not a choice, it is essential, and we will not be diverted from moving with the times."
London mayor Boris Johnson attacked the strike, labelling it a "political attack" on the government.
Writing in The Daily Telegraph, he said: "We need to take account of the fact that some ticket offices are now selling fewer than 10 tickets an hour. We need to liberate staff to get out on to the platforms and concourses where they can be of most use to the travelling public.
Further strikes
"We have come up with a way of doing this that keeps a ticket office at every station that currently possesses one, and, remarkably, given the colossal budgetary pressures we face, we are able to do this with no compulsory redundancies."
Two further strikes are planned for November if the dispute remains unresolved.
The RMT also banned its members from accepting overtime over the weekend in protest at the job cuts.
The strike can be followed on a BBC London Twitter feed and a live update web page.
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